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This formula is for specific health conditions. Consult your veterinarian before use.

Hill’s
Prescription Diet - Gastrointestinal Biome Stress Cat Food
Summary
Hill’s Prescription Diet Gastrointestinal Biome is a high-fiber dry cat food clinically shown to promote regular healthy stool in as little as 24 hours and help reduce the risk of recurrence of digestive upsets.
The first ingredient is Meat and Animal Derivatives (chicken 14%), providing the lead animal protein source, complemented by chicken and turkey meal for additional amino acids.
At 36% crude protein and 16.9% fat with a metabolizable energy of 3,786 kcal/kg, it offers a concentrated calorie profile that can sustain adult cats but calls for portion control in less active individuals.
Hill’s ActivBiome+ ingredient technology uses a targeted prebiotic blend to nourish the gut microbiome and stimulate beneficial postbiotics that normalize stool consistency.
Functional fibers such as dried beet pulp, ground pecan shell, and citrus pulp help regulate intestinal transit, improve fecal quality, and support a stable gut environment.
Flaxseed and fish oil supply omega-3s, including EPA (0.205%) and DHA (0.138%), which support gut mucosal integrity and a healthy inflammatory response.
Taurine at 0.21% supports heart and eye health, while antioxidants including vitamin E (706 IU/kg), vitamin C (117 mg/kg), and beta-carotene help protect tissues during periods of GI stress.
The mineral and electrolyte profile—calcium 0.79%, phosphorus 0.62%, magnesium 0.071%, potassium 0.87%, and sodium 0.29%—supports overall fluid and neuromuscular balance during digestive disturbances.
Carbohydrates from cereals, maize, and rice (NFE 30.7%) provide digestible energy, while fruit and seed ingredients contribute fermentable substrates and phytonutrients associated with gut health.
Formulated as a complete and highly digestible diet for adult cats, it is indicated for reducing intestinal absorptive disorders and compensating for maldigestion.
Nutrition
Ingredients
- Meat And Animal Derivatives (Chicken 14%)
- Cereals
- Vegetable Protein Extracts
- Derivatives Of Vegetable Origin
- Oils And Fats
- Fruit
- Minerals
- Seeds
- Milk And Milk Derivatives
- Chicken And Turkey Meal
- and also:
Vitamins and Additives
- Vitamin A 8948 IU
- Vitamin B1 24 mg/kg
- Vitamin B2 12 mg/kg
- Vitamin B3 144 mg/kg
- Vitamin B5 34.8 mg/kg
- Vitamin B6 9.9 mg/kg
- Vitamin B12 0.16 mg/kg
- Vitamin C 117 mg/kg
- Vitamin D 734 IU
- Vitamin D3 734 IU
- Vitamin E 706 mg/kg
- and also:
Guaranteed Analysis
Guaranteed Analysis
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Prescription Diet - Gastrointestinal Biome Stress Cat Food
Product changes
- Ingredients list changed
- Score changed from 53 -> 41
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How the score is calculated?
The actual calculation of the score is based on sophisticated and advanced algorithm that takes into account multiple parameters.
To simplify the explanation, the calculation is based on three main criteria:
(1) Amount of protein (more is better)
(2) Amount of carbohydrates (less is better)
(3) Quality and source of ingredients.
Based on that 3 main criteria, 9 score calculation rules are used to compare the different foods.
One major assumption is that the closer an ingredient is to the top of the ingredient list, the greater its relative weight and contribution to the food.
In general, cat food is composed of protein, fats, carbohydrates, fibers, vitamins, and minerals.
Protein is the most important component in a cat's diet, and cats primarily get their protein from animal meat.
Fat is a primary source of energy and essential fatty acids.
Carbohydrates are controversial in a cat's diet, as cats are obligate carnivores and typically consume very few carbohydrates.
Fibers play an important role in digestion and food absorption, and vitamins and minerals are essential for different organism functions.
Dry matter values are used to compare the amount of nutrients in different cat foods. This means that moisture is excluded from the equation to provide a more accurate comparison.
Putting all of these and more into a formula results in a product score.
The maximum score a cat food can receive is 100. Points are added or removed based on the score calculation rules.
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